Ivermectin | CoroFlu | Social distancing | Nasal vaccine | COVID-19

CoroFlu is  COVID-19 nasal vaccine that has been shown safe and efficacy data in humans, during phase 1 and phase2 and clinical trials. Bharat biotech is involved in the development and testing of this vaccine. This is an international collaboration project between the University of Wisconsin-Madison along with Flugen and  Bharat Biotech. Coroflu will be built on the backbone of FluGen’s vaccine candidate known as M2SR. Based on an invention by UW-Madison virologists and FluGen Co-founders(Yoshihiro and Gabriele). This is a self-limiting version of the influenza virus that induces an immune response against the flu.

Is Social distancing is followed only in humans or other species too?

Yes, Animals to have their own strategies of social distancing, for example, infected ants spend most of the time outside their nest, in order to avoid infection to other ants.  

In honey bee hives, infected larvae emit certain chemicals called bee-pheromones. Older bees have the capability to smell these pheromones. So, the older bees will separate the diseased bees from the hives.

The infected bees will take up honey as self antibiotics, if this doesn’t work they self isolate from the group of bees. 

In 1966, a chimpanzee named McGregor had contracted polio. Other members of the group removed from their crew. Once they get cured, they will be welcomed back.

During an infection, sick mice remove themselves from the group. Female mice can smell parasitic infection in the male’s urine.

In aquatic species such as Caribbean spiny lobsters emit certain chemical signals, which can be smelled by fellow lobsters at an early stage of infection. When a virus infects lobsters it takes up o 8 weeks to get infected. Their fellow lobsters avoid them during the first 4 weeks of infection.

In the case of the cow, they self isolate themselves before giving birth to a calf in order to prevent the disease from their calf. Female fish generally prefer parasite-free partners. In this case, they use visual clues and chemical signals to identify infected individuals. This has been observed in Trinidad guppies.

Possible drug identified  by Australian scientists for coronavirus

Ivermectin, An FDA the approved antiparasitic drug has shown good results in vitro against broad range diseases such as Dengue, influenza and Zika virus. Based on the study, available antiparasitic drugs can kill the virus within 48 hours. Now, the next step is to determine the dosage calculation for preclinical and clinical testings. The above study was conducted between Monash University and Doherty institute of infection and immunity.